Cell Lines and Cell Cultures
Amsbio LLC Lyophilized microvesicles from U87 GM cell line
Lyophilized microvesicles from U87 GM cell line
Eurofins Discoverx PrecisION hGABAA α6/β3/γ2 Recombinant Stable Cell Line, 2 vials. (CYL3086)
The PrecisION hGABAA α6/β3/γ2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying GABAA α6/β3/γ2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses GABAA α6/β3/γ2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Clostridioides difficile
This strain of Clostridioides difficile was isolated from a clinical specimen. It is toxigenic (toxinotype XII) and was confirmed by PCR to have the tcdA and tcdB genes. This product has applications in enteric disease and infectious disease research.
Eurofins Discoverx ChemiScreen Y2 Neuoropeptide Y Receptor Stable Cell Line, 2 vials. (HTS066C)
The ChemiScreen Y2 Neuropeptide Y Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NPY2R alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of NPY2R, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
iQ Biosciences Cynomolgus Monkey PBMCs, No Immunophenotyping, 5M cells/vial
High-quality, high-viability (> 90%) cynomolgus (cyno) monkey (or macaque) peripheral blood mononuclear cells (PBMCs) sourced responsibly from a vetted third party facility. Used for a wide variety of safety assessment and functional assays. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate number of vials from each individual donor - Donor(s) with a higher percentage of the cells of interest, i.e., B cells, CD14+ cells, CD4+ cells, CD8+ cells, or NK cells
Biochain Institute Inc Paraffin Tissue Section - Multiple Sclerosis Disease: Brain: Hippocampus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ORGANABIO LLC Human Peripheral Blood Mononuclear Cells (PBMCs) / Cryopreserved / Single Donor / 30-45x vials of 1x10E8 cells/vial / OrganaBio LEUKOPAC - PBMC / Research Use Only
Human peripheral blood mononuclear cells (PBMCs) from recallable / HLA-typed healthy adult donors isolated by density gradient centrifugation. Comprehensive characterization including immunophenotyping (CD45 / CD14 / CD19 / CD56 / CD3 / CD3CD4 / CD3CD8) / infectious disease testing / and high-resolution HLA typing (Class I and II). Half leukopak processed into vials. Availble in 1X10E8 cells/vial. OrganaBio Human PBMCs are isolated from peripheral blood of normal / healthy adult donors by density gradient centrifugation. Each lot is cryopreserved and characterized by immunophenotyping. Comprehensive donor characterization includes infectious disease testing panel and high-resolution HLA typing with full donor demographics (age / sex / BMI / race / ethnicity / blood type).
ATCC Streptococcus pneumoniae; Type 8; genomic DNA
Genomic DNA isolated from Streptococcus pneumoniae. This bacterial strain is also available as ATCC Catalog No. 6308™. Deposited as Diplococcus pneumoniae.
ATCC JeKo-1; Mantle Cell Lymphoma; Human (Homo sapiens)
The JeKo-1 mantle cell lymphoma (MCL) cell line was isolated from the peripheral blood mononuclear cells of a 78-year-old female with a large cell variant of MCL showing leukemic conversion. The JeKo-1 cells are highly tumorigenic in SCID mice and has applications for immunology research.
ATCC Synthetic Middle East; respiratory syndrome; coronavirus RNA
Quantitative synthetic RNA for Middle East respiratory syndrome coronavirus can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load and for other molecular biology applications. This preparation includes fragments from the ORF1ab, ORF5, upper envelope (upE), ORF8b, nucleocapsid (N) protein gene, and 3' UTR regions.
Amsbio LLC Human Endometrial cancer and normal adjacent tissue FFPE block
Human Endometrial cancer and normal adjacent tissue FFPE block
Promocell GmbH PromoCell NHEM.f-c 500,000 Human Epidermal Melanocytes, derived from foreskin, cryopreserved
Primary Normal Human Epidermal Melanocytes (NHEM) are isolated from the epidermis of juvenile foreskin.Melanocytes are located in the stratum basale, but branch out between the keratinocytes in suprabasal layers. About 5-10 % of the cells in the epidermis are melanocytes. The main purpose of melanocytes is the production of melanin, the protein responsible for the pigmentation of the skin, eyes, and hair. Melanin protects the cells in the skin and in deeper layers from the hazardous effects of UV radiation. It is produced and stored in melanosomes, which are located close to the melanocyte membrane, but it can also be transferred to neighboring keratinocytes.PromoCell Normal Human Epidermal Melanocytes are isolated using the PMA (Phorbol Myristate Acetate)-containing Melanocyte Growth Medium. Since PMA is a tumor promoting mitogen, it can interfere with experimental approaches. Therefore, we recommend using cells isolated in Melanocyte Growth Medium M3.
ATCC Moloney/4070A MuLV; Strain: pAMS
Hybrid Moloney/Amphotropic murine leukemia virus (Mo/A-MuLv) 4070A envelope strain is propagated in NIH/3T3 cells (ATCC CRL-1658). This strain was harvested from tk(-) NIH3T3 cells transfected with molecular clone of MLV cells (ATCC VR-1448). Use this virus in your analytical methodologies and pharmaceutical and personal care applications.
ATCC Pro-5; Ovary; Chinese Hamster (Cricetulus griseus)
Pro-5 is a cell line exhibiting epithelial-like morphology that was isolated from the ovary of a Chinese hamster. This cell line was deposited by P Stanley.
